Non-humanoid and Semi-human Heroes and Villains

The Amazing Three (W3 by Osamu Tezuka)

Annapuma and Unipuma (Dominion by Masamune Shirow)

Billy (Billy Dog or Billy Inu by Moto Abiko and Hiroshi Fujiwara)

Black Cat (Back Cat by Hideshi Hino)

Bookila (Say Hello to Bookila! by Osamu Tezuka)

Bomba (Bomba by Osamu Tezuka)

Bonobono (Bono Bono by Mikio Igarashi)

Bug Boy (The Bug Boy by Hideshi Hino)

Cutey Cat (Cotton Planet or Wata no Kuniboshi by Yumiko Oshima)

Dan (Brave Dan by Osamu Tezuka)

Doraemon (Doraemon by Moto Abiko and Hiroshi Fujiwara)

Gin (Silver Fang: Shooting Star Gin or Ginga: Nagareboshi Gin by Yoshihiro Takahashi) 

Goa (Ambassador Magma by Osamu Tezuka)

Godzilla (Various)

Gon (Gon by Masashi Tanaka)

Hamtaro Ham-Ham (The Adventures of Hamtaro or Tottoko Hamtaro by Ritsuko Kawai)

Hari and Ruri (Wish by CLAMP)

Harima (Phoenix: The Sun by Osamu Tezuka)

Inu-Yasha (Inu-Yasha by Rumiko Takahashi)

Jingoro (Kimagure Orange Road by Izumi Matsumoto)

Jinmen (Devilman by Go Nagai)

Aka Kabuto (Silver Fang: Shooting Star Gin or Ginga: Nagareboshi Gin by Yoshihiro Taahashi)

Kerberos (Card Captor Sakura by CLAMP)

Kiba (Wolf's Rain by Bones and Keiko Nobumoto)

Kimba a.k.a. Leo (Jungle Emperor or Jungle Taitei by Osamu Tezuka)

Kobayashimaru (Nakano Military Prep School by Koichiro Yasunaga)

Makemono (Urotsukodoji by Toshio Maeda)

Manmaru (Manmaru the Ninja Penguin or Ninpen Manmaru by Mikio Igarashi)

Mephist (Neo Faust by Osamu Tezuka)

Michael (What's Michael? by Makoto Kobayashi)

Mister Pen-Pen (Second Grader Magazine by Mayumi Muroyama)

Ichigo Momomiya (Tokyo MewMew by Mia Ikumi and Reiko Yoshida)

Mongrel Bow-Wow (Modern Dog Tales Bow-Wow or Heisei Inu Monogatari Bow Wow by Teryy Yamamoto)

Nao (Island of Cats or Neko no Shima by Miho Obana)

Norakuro (Norakuro by Shiho Tagawa)

Noriko (Purple Eyes in the Dark or Yami no Purple Eye by Chie Shinohara)

NukuNuku (All-Purpose Cultural Catgirl NukuNuku or Banno Bunka Neko Musume by Yuzo Takada)

Nyako (Nekojiru Noodles or Nekojiru Udon by Nekojiru)

Oyoyo (Mr. Happy or Shiawase-san by Misako Ishikawa)

"Perky" Perkins (Apocalypse Meow! or Cat Shit One by Motofumi Kobayashi)

Pero (Puss In Boots by Hayao Miyazaki)

Phoenix (Phoenix or Hi no Tori or Firebird by Osamu Tezuka)

Pikachu (Pokemon by Various)

Pyonyoshi (The Gutsy Frog or Dokonju Gaeru by Yasumi Yoshizawa)

Genma Saotome (Ranma or Ranma Nibbunnoichi by Rumiko Takahashi)

Takuji (3x3 Eyes or Sazan Eyes by Yuzo Takada)

Unico (Unico by Osamu Tezuka)

Wansa (Wansa-kun by Osamu Tezuka)

Weasel Spirits (Ushio and Tora by Kazuhiro Fujita)

The Zoids (Various)